BDBM50009568 (Thiocolchicine)N-(1,2,3-Trimethoxy-10-methylsulfanyl-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-acetamide::CHEMBL18981::N-((S)-1,2,3-Trimethoxy-10-methylsulfanyl-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-acetamide::N-(1,2,3-Trimethoxy-10-methylsulfanyl-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-acetamide::N-(1,2,3-Trimethoxy-10-methylsulfanyl-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-acetamide (Thiocolchicine)::N-(1,2,3-Trimethoxy-10-methylsulfanyl-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-acetamide(thiocolchicine)::THIOCOLCHICINE

SMILES: COc1cc2CC[C@H](NC(C)=O)c3cc(=O)c(SC)ccc3-c2c(OC)c1OC

InChI Key: InChIKey=CMEGANPVAXDBPL-UHFFFAOYSA-N

Data: 1 KI  8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50009568   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Similar to alpha-tubulin isoform 1 (Bovine)	BDBM50009568 ((Thiocolchicine)N-(1,2,3-Trimethoxy-10-methylsulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bovine)	BDBM50009568 ((Thiocolchicine)N-(1,2,3-Trimethoxy-10-methylsulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1/Tubulin beta-2B chain (Bovine)	BDBM50009568 ((Thiocolchicine)N-(1,2,3-Trimethoxy-10-methylsulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tubulin beta-2B chain (Bovine)	BDBM50009568 ((Thiocolchicine)N-(1,2,3-Trimethoxy-10-methylsulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Tubulin alpha-1A chain (Pig)	BDBM50009568 ((Thiocolchicine)N-(1,2,3-Trimethoxy-10-methylsulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	646	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bovine)	BDBM50009568 ((Thiocolchicine)N-(1,2,3-Trimethoxy-10-methylsulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bovine)	BDBM50009568 ((Thiocolchicine)N-(1,2,3-Trimethoxy-10-methylsulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bovine)	BDBM50009568 ((Thiocolchicine)N-(1,2,3-Trimethoxy-10-methylsulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Pig)	BDBM50009568 ((Thiocolchicine)N-(1,2,3-Trimethoxy-10-methylsulfa...) Show SMILES Show InChI	GoogleScholar	UniChem		700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair