BDBM50009672 AdoHcy::CHEMBL418052::S-(5'-adenosyl)-L-homocysteine::S-(5'-deoxyadenosin-5'-yl)-L-homocysteine::S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-ribofuranos-5-yl]-L-homocysteine::S-adenosyl-L-homocysteine::SAH::US8895245, S-Adenosyl-L-homocysteine (SAH)::US9175331, 1::US9333217, S-Adenosyl-L-homocysteine (SAH)

SMILES: N[C@@H](CCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O

InChI Key: InChIKey=ZJUKTBDSGOFHSH-UHFFFAOYSA-N

Data: 17 KI  83 IC50  6 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 106 hits for monomerid = 50009672   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	467	n/a	n/a	n/a	n/a	7.6	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	263	n/a	n/a	n/a	n/a	7.6	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	283	n/a	n/a	n/a	n/a	7.6	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	380	n/a	n/a	n/a	n/a	7.6	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	7.6	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	467	n/a	n/a	n/a	n/a	7.6	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 [Y641H] (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	263	n/a	n/a	n/a	n/a	7.6	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 [Y641S] (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	283	n/a	n/a	n/a	n/a	7.6	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 [Y641N] (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	380	n/a	n/a	n/a	n/a	7.6	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 [Y641F] (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	7.6	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 [Y641F] (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.66E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 [A677G] (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 [A687V] (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	467	n/a	n/a	n/a	n/a	7.6	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	263	n/a	n/a	n/a	n/a	7.6	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	283	n/a	n/a	n/a	n/a	7.6	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	380	n/a	n/a	n/a	n/a	7.6	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	7.6	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 1 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Methylosome protein 50/Protein arginine N-methyltransferase 5 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
tRNA (guanine-N(1)-)-methyltransferase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.01E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
tRNA (guanine-N(1)-)-methyltransferase (Staphylococcus aureus (strain NCTC 8325 / PS 47))	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
tRNA (guanine-N(1)-)-methyltransferase (Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA (cytosine-5)-methyltransferase 1 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 3 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT2 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase SUV39H2 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase SETD7 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA (cytosine-5)-methyltransferase 1 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase, H3 lysine-79 specific (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA (cytosine-5)-methyltransferase 1 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT2 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 3 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 7 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 3 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase NSD2 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
N6-adenosine-methyltransferase catalytic subunit (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase, H3 lysine-79 specific (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 1 (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
tRNA (cytosine(38)-C(5))-methyltransferase (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.36E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
tRNA (cytosine(38)-C(5))-methyltransferase (Human)	BDBM50009672 (AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair