BDBM50009777 (ponalrestat)[3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,4-dihydro-phthalazin-1-yl]-acetic acid::CHEMBL7679::Ponalrestat::Ponalrestat (statil)::[3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,4-dihydro-phthalazin-1-yl]-acetic acid::[3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,4-dihydro-phthalazin-1-yl]-acetic acid(ponalrestat)

SMILES: OC(=O)Cc1nn(Cc2ccc(Br)cc2F)c(=O)c2ccccc12

InChI Key: InChIKey=LKBFFDOJUKLQNY-UHFFFAOYSA-N

Data: 11 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50009777   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldo-keto reductase family 1 member B1 (Human)	BDBM50009777 (Ponalrestat (statil) | CHEMBL7679 | [3-(4-Bromo-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
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Aldo-keto reductase family 1 member B1 [K65Q] (Bovine)	BDBM50009777 (Ponalrestat (statil) | CHEMBL7679 | [3-(4-Bromo-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
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Aldo-keto reductase family 1 member B1 (Pig)	BDBM50009777 (Ponalrestat (statil) | CHEMBL7679 | [3-(4-Bromo-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
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Aldo-keto reductase family 1 member B1 [K65Q] (Bovine)	BDBM50009777 (Ponalrestat (statil) | CHEMBL7679 | [3-(4-Bromo-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
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Aldo-keto reductase family 1 member B1 (Human)	BDBM50009777 (Ponalrestat (statil) | CHEMBL7679 | [3-(4-Bromo-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	56.5	n/a	n/a	n/a	n/a	n/a	n/a
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Aldo-keto reductase family 1 member B1 (Rat)	BDBM50009777 (Ponalrestat (statil) | CHEMBL7679 | [3-(4-Bromo-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aldo-keto reductase family 1 member B1 (Rat)	BDBM50009777 (Ponalrestat (statil) | CHEMBL7679 | [3-(4-Bromo-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
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Aldo-keto reductase family 1 member A1 (Pig)	BDBM50009777 (Ponalrestat (statil) | CHEMBL7679 | [3-(4-Bromo-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rat)	BDBM50009777 (Ponalrestat (statil) | CHEMBL7679 | [3-(4-Bromo-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Rat)	BDBM50009777 (Ponalrestat (statil) | CHEMBL7679 | [3-(4-Bromo-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Human)	BDBM50009777 (Ponalrestat (statil) | CHEMBL7679 | [3-(4-Bromo-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	66.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair