BDBM50009844 2-fluorospiro[9H-fluorene-9,4'-(tetrahydro-1'H-imidazole)]-2',5'-dione::CHEMBL7480

SMILES Fc1ccc2-c3ccccc3C3(NC(=O)NC3=O)c2c1

InChI Key InChIKey=JRGBXEJDIMXJAP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50009844   

TargetAldo-keto reductase family 1 member A1(Sus scrofa)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009844(2-fluorospiro[9H-fluorene-9,4'-(tetrahydro-1'H-imi...)
Affinity DataIC50:  27nMAssay Description:Selectivity ratio measured as the IC50 ratio of aldehyde/aldose reductase valuesChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009844(2-fluorospiro[9H-fluorene-9,4'-(tetrahydro-1'H-imi...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity measured against rat lens aldose reductase using 3-pyridinecarboxaldehyde as substrateChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed