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BDBM50009863 CHEMBL273372::[2-Ethyl-1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl]-(4-methoxy-phenyl)-methanone

SMILES: CCc1c(C(=O)c2ccc(OC)cc2)c2ccccc2n1CCN1CCOCC1

InChI Key: InChIKey=NCQJQOTXLBQBMD-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50009863   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin-H2 D-isomerase


(Mus musculus)
BDBM50009863
PNG
(CHEMBL273372 | [2-Ethyl-1-(2-morpholin-4-yl-ethyl)...)
Show SMILES CCc1c(C(=O)c2ccc(OC)cc2)c2ccccc2n1CCN1CCOCC1
Show InChI InChI=1S/C24H28N2O3/c1-3-21-23(24(27)18-8-10-19(28-2)11-9-18)20-6-4-5-7-22(20)26(21)13-12-25-14-16-29-17-15-25/h4-11H,3,12-17H2,1-2H3
PDB
MMDB

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PC sid
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Similars

Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



Sterling Research Group

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% activity of prostaglandin synthetase was determined in vitro in mouse brain microsomes


J Med Chem 34: 1099-110 (1991)


Article DOI: 10.1021/jm00107a034
BindingDB Entry DOI: 10.7270/Q24M955S
More data for this
Ligand-Target Pair