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BDBM50009931 4-(2-Methoxy-ethyl)-1-phenyl-pyrazolidin-3-one::CHEMBL291227

SMILES: COCCC1CN(NC1=O)c1ccccc1

InChI Key: InChIKey=JCJXJRYNFQOFBM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50009931   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Rattus norvegicus)
BDBM50009931
PNG
(4-(2-Methoxy-ethyl)-1-phenyl-pyrazolidin-3-one | C...)
Show SMILES COCCC1CN(NC1=O)c1ccccc1
Show InChI InChI=1S/C12H16N2O2/c1-16-8-7-10-9-14(13-12(10)15)11-5-3-2-4-6-11/h2-6,10H,7-9H2,1H3,(H,13,15)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 350n/an/an/an/an/an/a



Sterling Research Group

Curated by ChEMBL


Assay Description
In vitro inhibition of rat 5-Lipoxygenase


J Med Chem 34: 1560-70 (1991)


Article DOI: 10.1021/jm00109a006
BindingDB Entry DOI: 10.7270/Q2RV0MPG
More data for this
Ligand-Target Pair
Arachidonate 5-lipoxygenase


(Rattus norvegicus)
BDBM50009931
PNG
(4-(2-Methoxy-ethyl)-1-phenyl-pyrazolidin-3-one | C...)
Show SMILES COCCC1CN(NC1=O)c1ccccc1
Show InChI InChI=1S/C12H16N2O2/c1-16-8-7-10-9-14(13-12(10)15)11-5-3-2-4-6-11/h2-6,10H,7-9H2,1H3,(H,13,15)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 480n/an/an/an/an/an/a



Sterling Research Group

Curated by ChEMBL


Assay Description
In vitro inhibition of rat 5-Lipoxygenase


J Med Chem 34: 1560-70 (1991)


Article DOI: 10.1021/jm00109a006
BindingDB Entry DOI: 10.7270/Q2RV0MPG
More data for this
Ligand-Target Pair