BDBM50010033 2-[3-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-propyl]-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL418911

SMILES O=S1(=O)N(CCCN2CCN(CC2)c2noc3ccccc23)c2cccc3cccc1c23

InChI Key InChIKey=DAWLQXVXJZJFFV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50010033   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
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Curated by ChEMBL
LigandPNGBDBM50010033(2-[3-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-prop...)
Affinity DataIC50:  990nMAssay Description:The concentration required to inhibit [3H]spiperone binding to dopamine receptor D2 in rat brain membranes (in vitro)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
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Curated by ChEMBL
LigandPNGBDBM50010033(2-[3-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-prop...)
Affinity DataIC50:  144nMAssay Description:The concentration required to inhibit [3H]prazosin binding to Alpha-1 adrenergic receptor in rat brain membranes was measured (in vitro)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
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Curated by ChEMBL
LigandPNGBDBM50010033(2-[3-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-prop...)
Affinity DataIC50:  2.30nMAssay Description:The concentration required to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat brain membranes (in vitro)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed