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BDBM50010072 CHEMBL318673::[3-(5-oxabicyclo[2.2.1],3-formaldehyde (anilinocarbonyl)hydrazone-hept-2-ylmethyl)phenoxy]acetic acid

SMILES: OC(=O)COc1cccc(CC2C3CCC(O3)C2C=NNC(=O)Nc2ccccc2)c1

InChI Key: InChIKey=JFLGDEPZDPAZLY-UHFFFAOYSA-N

Data: 1 Kd

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50010072   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50010072
PNG
(CHEMBL318673 | [3-(5-oxabicyclo[2.2.1],3-formaldeh...)
Show SMILES OC(=O)COc1cccc(CC2C3CCC(O3)C2C=NNC(=O)Nc2ccccc2)c1
Show InChI InChI=1S/C23H25N3O5/c27-22(28)14-30-17-8-4-5-15(11-17)12-18-19(21-10-9-20(18)31-21)13-24-26-23(29)25-16-6-2-1-3-7-16/h1-8,11,13,18-21H,9-10,12,14H2,(H,27,28)(H2,25,26,29)
UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 1.20E+3n/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
The compound was tested for inhibition of specific binding of [3H]-SQ 29,548 to thromboxane A2 receptor in human platelet membranes


J Med Chem 34: 2882-91 (1991)


Article DOI: 10.1021/jm00113a030
BindingDB Entry DOI: 10.7270/Q2CJ8CFZ
More data for this
Ligand-Target Pair