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BDBM50010149 CHEMBL323179::{2-Butyl-5-chloro-3-[8-(1H-tetrazol-5-yl)-naphthalen-2-ylmethyl]-3H-imidazol-4-yl}-methanol

SMILES: CCCCc1nc(Cl)c(CO)n1Cc1ccc2cccc(-c3nnn[nH]3)c2c1

InChI Key: InChIKey=BFZAZZKUIPENSW-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50010149   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II AT1B


(RAT)
BDBM50010149
PNG
(CHEMBL323179 | {2-Butyl-5-chloro-3-[8-(1H-tetrazol...)
Show SMILES CCCCc1nc(Cl)c(CO)n1Cc1ccc2cccc(-c3nnn[nH]3)c2c1
Show InChI InChI=1S/C20H21ClN6O/c1-2-3-7-18-22-19(21)17(12-28)27(18)11-13-8-9-14-5-4-6-15(16(14)10-13)20-23-25-26-24-20/h4-6,8-10,28H,2-3,7,11-12H2,1H3,(H,23,24,25,26)
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PC sid
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Article
PubMed
n/an/a 5.50E+4n/an/an/an/an/an/a



Ciba Geigy Limited

Curated by ChEMBL


Assay Description
Binding affinity against angiotensin II receptor in rat smooth muscle cell preparations


J Med Chem 34: 3105-14 (1991)


Article DOI: 10.1021/jm00114a021
BindingDB Entry DOI: 10.7270/Q27S7MRP
More data for this
Ligand-Target Pair