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BDBM50010150 CHEMBL107862::{2-Butyl-5-chloro-3-[5-(1H-tetrazol-5-yl)-naphthalen-1-ylmethyl]-3H-imidazol-4-yl}-methanol

SMILES: CCCCc1nc(Cl)c(CO)n1Cc1cccc2c(cccc12)-c1nnn[nH]1

InChI Key: InChIKey=SXSVYJMURHZZEB-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50010150   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II AT1B


(RAT)
BDBM50010150
PNG
(CHEMBL107862 | {2-Butyl-5-chloro-3-[5-(1H-tetrazol...)
Show SMILES CCCCc1nc(Cl)c(CO)n1Cc1cccc2c(cccc12)-c1nnn[nH]1
Show InChI InChI=1S/C20H21ClN6O/c1-2-3-10-18-22-19(21)17(12-28)27(18)11-13-6-4-8-15-14(13)7-5-9-16(15)20-23-25-26-24-20/h4-9,28H,2-3,10-12H2,1H3,(H,23,24,25,26)
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Similars

Article
PubMed
n/an/a 1.10E+3n/an/an/an/an/an/a



Ciba Geigy Limited

Curated by ChEMBL


Assay Description
Binding affinity against angiotensin II receptor in rat smooth muscle cell preparations


J Med Chem 34: 3105-14 (1991)


Article DOI: 10.1021/jm00114a021
BindingDB Entry DOI: 10.7270/Q27S7MRP
More data for this
Ligand-Target Pair