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BDBM50010615 3-(3,6,7,8,9,9a-Hexahydro-4H-quinolizin-1-yl)-phenol::CHEMBL7449

SMILES: Oc1cccc(c1)C1=CCCN2CCCCC12

InChI Key: InChIKey=UTPPZLWOQNHIMZ-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50010615   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a)


(Rattus norvegicus (rat))
BDBM50010615
PNG
(3-(3,6,7,8,9,9a-Hexahydro-4H-quinolizin-1-yl)-phen...)
Show SMILES Oc1cccc(c1)C1=CCCN2CCCCC12
Show InChI InChI=1S/C15H19NO/c17-13-6-3-5-12(11-13)14-7-4-10-16-9-2-1-8-15(14)16/h3,5-7,11,15,17H,1-2,4,8-10H2
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KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 320n/an/an/an/an/an/a



University of Lund

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]-spiperone binding to Dopamine receptor D2 in rat striatal membranes


J Med Chem 33: 1015-22 (1990)


Article DOI: 10.1021/jm00165a020
BindingDB Entry DOI: 10.7270/Q2PV6JBT
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50010615
PNG
(3-(3,6,7,8,9,9a-Hexahydro-4H-quinolizin-1-yl)-phen...)
Show SMILES Oc1cccc(c1)C1=CCCN2CCCCC12
Show InChI InChI=1S/C15H19NO/c17-13-6-3-5-12(11-13)14-7-4-10-16-9-2-1-8-15(14)16/h3,5-7,11,15,17H,1-2,4,8-10H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 5.30E+3n/an/an/an/an/an/a



University of Lund

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]-spiperone binding to Dopamine receptor D2 in rat striatal membranes


J Med Chem 33: 1015-22 (1990)


Article DOI: 10.1021/jm00165a020
BindingDB Entry DOI: 10.7270/Q2PV6JBT
More data for this
Ligand-Target Pair