BDBM50010927 2-Cyano-4-{4-[(2,4-diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid::CHEMBL65620

SMILES CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)NC(CC(C#N)C(O)=O)C(O)=O

InChI Key InChIKey=QTJFCMAGIDQVPI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50010927   

TargetDihydrofolate reductase(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50010927(2-Cyano-4-{4-[(2,4-diamino-pteridin-6-ylmethyl)-me...)
Affinity DataIC50:  57nMAssay Description:Ability to inhibit purified Dihydrofolate reductase from human leukemic lymphoblasts was determined spectrophotometrically at 340 nM.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed