BDBM50010961 2-Methyl-3-pyridin-3-ylmethyl-[1,4]naphthoquinone::CHEMBL92863

SMILES CC1=C(Cc2cccnc2)C(=O)c2ccccc2C1=O

InChI Key InChIKey=WLIXDRCIBTVQMR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50010961   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50010961(2-Methyl-3-pyridin-3-ylmethyl-[1,4]naphthoquinone ...)
Affinity DataIC50:  82nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50010961(2-Methyl-3-pyridin-3-ylmethyl-[1,4]naphthoquinone ...)
Affinity DataIC50:  490nMAssay Description:Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed