BDBM50010968 3-(2,5-Dimethyl-3,6-dioxo-4-pyridin-3-ylmethyl-cyclohexa-1,4-dienyl)-acrylic acid ethyl ester::CHEMBL93899

SMILES CCOC(=O)C=Cc1c(O)c(=C)c(Cc2cccnc2)c(O)c1=C

InChI Key InChIKey=FHHOFEFBBLNBGG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50010968   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50010968(3-(2,5-Dimethyl-3,6-dioxo-4-pyridin-3-ylmethyl-cyc...)
Affinity DataIC50:  8nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed