BDBM50010970 7-Pyridin-3-yl-7-(2,4,5-trimethyl-3,6-dioxo-cyclohexa-1,4-dienyl)-heptanoic acid::CHEMBL420251

SMILES Cc1c(C)c(O)c(C(=CCCCCC(O)=O)c2cccnc2)c(C)c1O

InChI Key InChIKey=VFJRBCKYVQINBK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50010970   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50010970(7-Pyridin-3-yl-7-(2,4,5-trimethyl-3,6-dioxo-cycloh...)
Affinity DataIC50:  9.30E+3nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50010970(7-Pyridin-3-yl-7-(2,4,5-trimethyl-3,6-dioxo-cycloh...)
Affinity DataIC50:  63nMAssay Description:Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed