BDBM50011232 CHEMBL3260332

SMILES CCOc1ccc(cc1)-n1nnc2nc(Nc3ccn(CCCC4CCNCC4)n3)ncc12

InChI Key InChIKey=NDPRRSMLHQJIAR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50011232   

TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50011232(CHEMBL3260332)
Affinity DataIC50: <300nMAssay Description:Inhibition of GCN2 (unknown origin) using GFP-elF2a as substrate preincubated with substrate for 20 mins measured after 90 mins by Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50011232(CHEMBL3260332)
Affinity DataIC50: <300nMAssay Description:Inhibition of GCN2-mediated elF2alpha phosphorylation in human U2OS cells after 2 hrs by immunocytochemistryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed