BDBM50011236 CHEMBL344314::Isoquinoline-5-sulfonic acid (2-amino-ethyl)-amide::Isoquinolinesulfonamide, H-9::N-(2-aminoethyl)isoquinoline-5-sulfonamide

SMILES: c1cc2cnccc2c(c1)S(=O)(=O)NCCN

InChI Key: InChIKey=DCVZSHVZGVWQKV-UHFFFAOYSA-N

Data: 8 IC50

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50011236   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase I isoform alpha (Human)	BDBM50011236 (Isoquinoline-5-sulfonic acid (2-amino-ethyl)-amide...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+5	n/a	n/a	n/a	n/a	7.4	30
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Casein kinase II subunit alpha (Human)	BDBM50011236 (Isoquinoline-5-sulfonic acid (2-amino-ethyl)-amide...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	7.4	30
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Protein kinase C alpha type (Human)	BDBM50011236 (Isoquinoline-5-sulfonic acid (2-amino-ethyl)-amide...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	7.4	30
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cAMP-dependent protein kinase type I-alpha regulatory subunit (Bovine)	BDBM50011236 (Isoquinoline-5-sulfonic acid (2-amino-ethyl)-amide...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	7.4	30
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Calcium/calmodulin-dependent protein kinase II inhibitor 2 (Bovine)	BDBM50011236 (Isoquinoline-5-sulfonic acid (2-amino-ethyl)-amide...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a	7.4	30
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MO15-related protein kinase Pfmrk (malaria parasite P. falciparum)	BDBM50011236 (Isoquinoline-5-sulfonic acid (2-amino-ethyl)-amide...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-dependent protein kinase catalytic subunit gamma (Human)	BDBM50011236 (Isoquinoline-5-sulfonic acid (2-amino-ethyl)-amide...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Human)	BDBM50011236 (Isoquinoline-5-sulfonic acid (2-amino-ethyl)-amide...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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