BDBM50011397 8-Methyl-3-(3-nitro-phenylcarbamoyloxy)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL159325

SMILES COC(=O)C1C2CC[C@H](C[C@@H]1OC(=O)Nc1cccc(c1)[N+]([O-])=O)N2C

InChI Key InChIKey=FFGDCGSTWMKRRN-CMAYJEJSSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50011397   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50011397(8-Methyl-3-(3-nitro-phenylcarbamoyloxy)-8-aza-bicy...)
Affinity DataIC50:  178nMAssay Description:Inhibition of [3H]dopamine uptake at dopamine transporter.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50011397(8-Methyl-3-(3-nitro-phenylcarbamoyloxy)-8-aza-bicy...)
Affinity DataIC50:  37nMAssay Description:Inhibition of [3H]cocaine binding to the dopamine transporter.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50011397(8-Methyl-3-(3-nitro-phenylcarbamoyloxy)-8-aza-bicy...)
Affinity DataIC50:  330nMAssay Description:Inhibition of [3H]GBR-12935 binding to the dopamine transporter.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(BOVINE)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50011397(8-Methyl-3-(3-nitro-phenylcarbamoyloxy)-8-aza-bicy...)
Affinity DataIC50:  37nMAssay Description:In vitro inhibitory activity towards [3H]cocaine binding to rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed