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BDBM50011418 2-(4-Amino-phenyl)-6-hydroxy-chromen-4-one::2-(4-aminophenyl)-6-hydroxy-4H-chromen-4-one::4'-amino-6-hydroxyflavone::CHEMBL166851

SMILES: Nc1ccc(cc1)-c1cc(=O)c2cc(O)ccc2o1

InChI Key: InChIKey=YBQRUOMICVULNM-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50011418   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
SRC


(Homo sapiens (human))
BDBM50011418
PNG
(2-(4-Amino-phenyl)-6-hydroxy-chromen-4-one | 2-(4-...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2cc(O)ccc2o1
Show InChI InChI=1S/C15H11NO3/c16-10-3-1-9(2-4-10)15-8-13(18)12-7-11(17)5-6-14(12)19-15/h1-8,17H,16H2
PDB
MMDB

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PC sid
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Similars

Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of p56 lck


J Nat Prod 55: 1529-1560 (1992)


Article DOI: 10.1021/np50089a001
BindingDB Entry DOI: 10.7270/Q2J966CC
More data for this
Ligand-Target Pair
SRC


(Homo sapiens (human))
BDBM50011418
PNG
(2-(4-Amino-phenyl)-6-hydroxy-chromen-4-one | 2-(4-...)
Show SMILES Nc1ccc(cc1)-c1cc(=O)c2cc(O)ccc2o1
Show InChI InChI=1S/C15H11NO3/c16-10-3-1-9(2-4-10)15-8-13(18)12-7-11(17)5-6-14(12)19-15/h1-8,17H,16H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.20E+3n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Ability to inhibit protein-tyrosine kinase activity of p56lck (isolated from bovine thymus) in vitro.


J Med Chem 34: 798-806 (1991)


Article DOI: 10.1021/jm00106a047
BindingDB Entry DOI: 10.7270/Q2CF9P3J
More data for this
Ligand-Target Pair