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BDBM50011428 2-(3,4,5-Trimethoxy-phenyl)-chromen-4-one::2-(3,4,5-trimethoxyphenyl)-4H-chromen-4-one::CHEMBL307856

SMILES: COc1cc(cc(OC)c1OC)-c1cc(=O)c2ccccc2o1

InChI Key: InChIKey=QCXAJQVDUHKDEL-UHFFFAOYSA-N

Data: 2 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50011428   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
SRC


(Homo sapiens (human))
BDBM50011428
PNG
(2-(3,4,5-Trimethoxy-phenyl)-chromen-4-one | 2-(3,4...)
Show SMILES COc1cc(cc(OC)c1OC)-c1cc(=O)c2ccccc2o1
Show InChI InChI=1S/C18H16O5/c1-20-16-8-11(9-17(21-2)18(16)22-3)15-10-13(19)12-6-4-5-7-14(12)23-15/h4-10H,1-3H3
PDB
MMDB

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Similars

Article
PubMed
n/an/a>8n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of p56 lck


J Nat Prod 55: 1529-1560 (1992)


Article DOI: 10.1021/np50089a001
BindingDB Entry DOI: 10.7270/Q2J966CC
More data for this
Ligand-Target Pair
SRC


(Homo sapiens (human))
BDBM50011428
PNG
(2-(3,4,5-Trimethoxy-phenyl)-chromen-4-one | 2-(3,4...)
Show SMILES COc1cc(cc(OC)c1OC)-c1cc(=O)c2ccccc2o1
Show InChI InChI=1S/C18H16O5/c1-20-16-8-11(9-17(21-2)18(16)22-3)15-10-13(19)12-6-4-5-7-14(12)23-15/h4-10H,1-3H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>2.00E+6n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Ability to inhibit protein-tyrosine kinase activity of p56lck (isolated from bovine thymus) in vitro.


J Med Chem 34: 798-806 (1991)


Article DOI: 10.1021/jm00106a047
BindingDB Entry DOI: 10.7270/Q2CF9P3J
More data for this
Ligand-Target Pair