BDBM50011936 2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-pyridin-3-yl-propyl ester::CHEMBL36649

SMILES Oc1ccc(\C=C(/C#N)C(=O)OCCCc2cccnc2)cc1O

InChI Key InChIKey=YXYJIJRAAWHSIH-OQLLNIDSSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50011936   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011936(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-py...)
Affinity DataIC50:  470nMAssay Description:Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011936(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-py...)
Affinity DataIC50:  3.93E+3nMAssay Description:Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011936(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed