BDBM50012346 CHEMBL70003::N-(2-{4-[2-Oxo-2-(6-oxo-5,6-dihydro-benzo[e]pyrido[3,2-b][1,4]diazepin-11-yl)-ethyl]-piperazin-1-yl}-ethyl)-acetamide

SMILES CC(=O)NCCN1CCN(CC(=O)N2c3ccccc3C(=O)Nc3cccnc23)CC1

InChI Key InChIKey=VQDPSXHKOQSFTH-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50012346   

LigandPNGBDBM50012346(CHEMBL70003 | N-(2-{4-[2-Oxo-2-(6-oxo-5,6-dihydro-...)
Affinity DataKi:  670nMAssay Description:Inhibition of binding of [3H]N-Methyl-scopolamine to Muscarinic acetylcholine receptor M1 of transfected A9L cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50012346(CHEMBL70003 | N-(2-{4-[2-Oxo-2-(6-oxo-5,6-dihydro-...)
Affinity DataKi:  970nMAssay Description:Inhibition of binding of [3H]N-methylscopolamine to muscarinic acetylcholine receptor M3 of transfected rat A9L cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50012346(CHEMBL70003 | N-(2-{4-[2-Oxo-2-(6-oxo-5,6-dihydro-...)
Affinity DataKi:  2.52E+3nMAssay Description:The compound was tested for the inhibition of binding of [3H]N-Methyl-scopolamine to muscarinic acetylcholine receptor M2 of rat heart tissue membran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50012346(CHEMBL70003 | N-(2-{4-[2-Oxo-2-(6-oxo-5,6-dihydro-...)
Affinity DataKi:  2.57E+3nMAssay Description:Inhibition of binding of [3H]N-Methyl-scopolamine to Muscarinic acetylcholine receptor M4 of NG108-15 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed