BDBM50012679 2-Methyl-naphthalen-1-ol::CHEMBL122451

SMILES Cc1ccc2ccccc2c1O

InChI Key InChIKey=SRJCJJKWVSSELL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50012679   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50012679(CHEMBL122451 | 2-Methyl-naphthalen-1-ol)
Affinity DataIC50: 130nMAssay Description:Ability to inhibit 5-lipoxygenase by using a crude preparation of the cytosolic enzyme from the rat basophilic leukemia (RBL-1) cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50012679(CHEMBL122451 | 2-Methyl-naphthalen-1-ol)
Affinity DataIC50: 130nMAssay Description:Inhibition of 5-lipoxygenase in Rattus norvegicus Rat basophil leukemia cells (RBL) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetProstaglandin G/H synthase 1/2(Bovine)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50012679(CHEMBL122451 | 2-Methyl-naphthalen-1-ol)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase in BSV cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed