BDBM50012905 CHEMBL3261331::US20240059676, Compound MGL-3196::USRE46024, 8

SMILES: CC(C)c1cc(Oc2c(Cl)cc(cc2Cl)-n2nc(C#N)c(=O)[nH]c2=O)n[nH]c1=O

InChI Key: InChIKey=FDBYIYFVSAHJLY-UHFFFAOYSA-N

Data: 4 IC50  9 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50012905   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyroid hormone receptor beta (Human)	BDBM50012905 (CHEMBL3261331 | USRE46024, 8 | US20240059676, Comp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	73	n/a	n/a	n/a	n/a
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Thyroid hormone receptor beta (Human)	BDBM50012905 (CHEMBL3261331 | USRE46024, 8 | US20240059676, Comp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	210	n/a	n/a	n/a	n/a
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Thyroid hormone receptor alpha (Human)	BDBM50012905 (CHEMBL3261331 | USRE46024, 8 | US20240059676, Comp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.74E+3	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50012905 (CHEMBL3261331 | USRE46024, 8 | US20240059676, Comp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A5 (Human)	BDBM50012905 (CHEMBL3261331 | USRE46024, 8 | US20240059676, Comp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50012905 (CHEMBL3261331 | USRE46024, 8 | US20240059676, Comp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50012905 (CHEMBL3261331 | USRE46024, 8 | US20240059676, Comp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Thyroid hormone receptor beta (Human)	BDBM50012905 (CHEMBL3261331 | USRE46024, 8 | US20240059676, Comp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.37E+3	n/a	n/a	n/a	n/a
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Thyroid hormone receptor alpha (Human)	BDBM50012905 (CHEMBL3261331 | USRE46024, 8 | US20240059676, Comp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.93E+3	n/a	n/a	n/a	n/a
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Retinoic acid receptor RXR-alpha [225-462]/Thyroid hormone receptor beta [148-410] (Human)	BDBM50012905 (CHEMBL3261331 | USRE46024, 8 | US20240059676, Comp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	192	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyroid hormone receptor alpha (Human)	BDBM50012905 (CHEMBL3261331 | USRE46024, 8 | US20240059676, Comp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	934	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyroid hormone receptor beta (Human)	BDBM50012905 (CHEMBL3261331 | USRE46024, 8 | US20240059676, Comp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	990	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyroid hormone receptor alpha (Human)	BDBM50012905 (CHEMBL3261331 | USRE46024, 8 | US20240059676, Comp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.85E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyroid hormone receptor beta (Human)	BDBM50012905 (CHEMBL3261331 | USRE46024, 8 | US20240059676, Comp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	167	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyroid hormone receptor alpha (Human)	BDBM50012905 (CHEMBL3261331 | USRE46024, 8 | US20240059676, Comp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.74E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyroid hormone receptor beta (Human)	BDBM50012905 (CHEMBL3261331 | USRE46024, 8 | US20240059676, Comp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyroid hormone receptor alpha (Human)	BDBM50012905 (CHEMBL3261331 | USRE46024, 8 | US20240059676, Comp...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair