BDBM50012925 2-Amino-6-(1-{1-cyclohexylmethyl-2-hydroxy-4-[2-(8-isobutyl-6-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-yl)-3-pyridin-3-yl-propionylamino]-4-oxo-butylcarbamoyl}-3-methyl-butylamino)-hexanoic acid . 4H2O::CHEMBL424423

SMILES CC(C)CC(NCCCC[C@H](N)C(O)=O)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)CC(=O)NC(=O)C(Cc1cccnc1)c1nnc2c(CC(C)C)nc(cn12)-c1ccccc1

InChI Key InChIKey=ZCEZSSVRVOFGQC-DXKTUJFCSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50012925   

TargetRenin(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012925(2-Amino-6-(1-{1-cyclohexylmethyl-2-hydroxy-4-[2-(8...)
Affinity DataIC50:  3.70nMAssay Description:Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed