BDBM50013091 2-(3,4-Dichloro-phenylamino)-1,9-dihydro-purin-6-one::CHEMBL51613
SMILES Clc1ccc(Nc2nc3nc[nH]c3c(=O)[nH]2)cc1Cl
InChI Key InChIKey=RZBANNTZMKJFNR-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50013091
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against HSV-1 thymidine kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of TdR phosphorylation using thymidine kinase assay for herpes simplex virus type 2More data for this Ligand-Target Pair
TargetThymidine kinase(Human herpesvirus 1)
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of TdR phosphorylation using thymidine kinase assay for herpes simplex virus type 1More data for this Ligand-Target Pair
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Stanford University Medical School
Curated by ChEMBL
Stanford University Medical School
Curated by ChEMBL
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition against DNA polymerase by direct assay with activated DNA and 25 uM dNTPs lacking the expected competitor substrateMore data for this Ligand-Target Pair
TargetThymidine kinase(Human herpesvirus 2)
University Of Massachusetts Medical School
Curated by ChEMBL
University Of Massachusetts Medical School
Curated by ChEMBL
Affinity DataIC50: 3.02E+4nMAssay Description:Inhibitory activity against HSV-2 thymidine kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
TargetDNA primase(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
Stanford University Medical School
Curated by ChEMBL
Stanford University Medical School
Curated by ChEMBL
Affinity DataIC50: 880nMAssay Description:Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cellsMore data for this Ligand-Target Pair
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Stanford University Medical School
Curated by ChEMBL
Stanford University Medical School
Curated by ChEMBL
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition against DNA polymerase by direct assay with activated DNA and 25 uM dNTPs lacking the expected competitor substrateMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition against DNA topoisomerase I by direct assay with activated DNA and 25 uM dNTPs including [3H]-dTTPMore data for this Ligand-Target Pair
TargetDNA primase(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
Stanford University Medical School
Curated by ChEMBL
Stanford University Medical School
Curated by ChEMBL
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition against Primase by coupled primase-DNA polymerase-I assay with the two subunit recombinant HSV-1 helicase primaseMore data for this Ligand-Target Pair