BDBM50013204 CHEMBL343158::Thiophene-3-carboxylic acid [5-(2-fluoro-phenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylmethyl]-amide

SMILES Fc1ccccc1C1=NC(CNC(=O)c2ccsc2)CNc2ccccc12

InChI Key InChIKey=AADSIEWMSHPCSV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50013204   

LigandPNGBDBM50013204(CHEMBL343158 | Thiophene-3-carboxylic acid [5-(2-f...)
Affinity DataIC50:  93nMAssay Description:Evaluated for its concentration required for displacement of [3H]-Naloxone from opioid receptors in rat brain tissuesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013204(CHEMBL343158 | Thiophene-3-carboxylic acid [5-(2-f...)
Affinity DataIC50:  7.40E+4nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type B receptor in guinea pig brain tissuesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013204(CHEMBL343158 | Thiophene-3-carboxylic acid [5-(2-f...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed