BDBM50013204 CHEMBL343158::Thiophene-3-carboxylic acid [5-(2-fluoro-phenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylmethyl]-amide
SMILES Fc1ccccc1C1=NC(CNC(=O)c2ccsc2)CNc2ccccc12
InChI Key InChIKey=AADSIEWMSHPCSV-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50013204
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 93nMAssay Description:Evaluated for its concentration required for displacement of [3H]-Naloxone from opioid receptors in rat brain tissuesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type B receptor in guinea pig brain tissuesMore data for this Ligand-Target Pair
TargetCholecystokinin receptor type A(RAT)
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair