BDBM50013221 CHEMBL163277::Sodium salt of7-[4-(4-Fluoro-phenyl)-1-isopropyl-2-methyl-1H-pyrrol-3-yl]-3,5-dihydroxy-heptanoic acid
SMILES CC(C)n1cc(c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c1C)-c1ccc(F)cc1
InChI Key InChIKey=LJBGBXVAGFAMLZ-QZTJIDSGSA-M
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50013221
Affinity DataIC50: 0.270nMAssay Description:Inhibition of cellular HMG-CoA reductase in cultures of hepatic cells (HEP G2, a human hepatoma cell line)More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst
Curated by ChEMBL
Hoechst
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:In vitro inhibition of HMG-CoA reductase of rat liverMore data for this Ligand-Target Pair