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BDBM50013238 1-o-Tolyl-1,3-dihydro-imidazo[4,5-c]quinoline-2-thione::CHEMBL356246

SMILES: Cc1ccccc1-n1c2c(cnc3ccccc23)[nH]c1=S

InChI Key: InChIKey=ZBBOEODUROWEBS-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50013238   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Na/K-ATPase


(Sus scrofa (Pig))
BDBM50013238
PNG
(1-o-Tolyl-1,3-dihydro-imidazo[4,5-c]quinoline-2-th...)
Show SMILES Cc1ccccc1-n1c2c(cnc3ccccc23)[nH]c1=S
Show InChI InChI=1S/C17H13N3S/c1-11-6-2-5-9-15(11)20-16-12-7-3-4-8-13(12)18-10-14(16)19-17(20)21/h2-10H,1H3,(H,19,21)
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.20E+4n/an/an/an/an/an/a



Smith Kline & French Research Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibition of H+/K+ ATPase activity was determined in gastric vesicles of pig using ATPase assay with pH 7


J Med Chem 33: 527-33 (1990)


Article DOI: 10.1021/jm00164a010
BindingDB Entry DOI: 10.7270/Q2Z31XND
More data for this
Ligand-Target Pair