BDBM50013538 4-[3-(Quinolin-2-ylmethoxy)-phenoxy]-butyric acid::CHEMBL18471

SMILES OC(=O)CCCOc1cccc(OCc2ccc3ccccc3n2)c1

InChI Key InChIKey=HYTBIVFDTLBKQS-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50013538   

TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50013538(4-[3-(Quinolin-2-ylmethoxy)-phenoxy]-butyric acid ...)
Affinity DataKi:  130nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50013538(4-[3-(Quinolin-2-ylmethoxy)-phenoxy]-butyric acid ...)
Affinity DataKi:  130nMAssay Description:In vitro binding affinity against cysteinyl leukotriene D4 receptor from guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50013538(4-[3-(Quinolin-2-ylmethoxy)-phenoxy]-butyric acid ...)
Affinity DataIC50:  240nMAssay Description:Inhibition of the spasmogenic activity of LTD4 in guinea pig parenchymal strips.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed