BindingDB logo
myBDB logout

BDBM50013998 CHEMBL3260528

SMILES: CCOC(=O)C(C)(Cc1ccccc1)c1ccnc2c(cnn12)-c1cccc(Cl)c1

InChI Key: InChIKey=AANQFGKCUNPFMY-UHFFFAOYNA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50013998   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G-protein coupled receptor 119 (GPR119)


(Homo sapiens (Human))
BDBM50013998
PNG
(CHEMBL3260528)
Show SMILES CCOC(=O)C(C)(Cc1ccccc1)c1ccnc2c(cnn12)-c1cccc(Cl)c1
Show InChI InChI=1/C24H22ClN3O2/c1-3-30-23(29)24(2,15-17-8-5-4-6-9-17)21-12-13-26-22-20(16-27-28(21)22)18-10-7-11-19(25)14-18/h4-14,16H,3,15H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 130n/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 overexpressed in CHO cells assessed as stimulation of cAMP production by HTRF assay


Bioorg Med Chem Lett 24: 2383-7 (2014)


Article DOI: 10.1016/j.bmcl.2014.03.023
BindingDB Entry DOI: 10.7270/Q2KP83P1
More data for this
Ligand-Target Pair