BDBM50014237 6-(4-Methylsulfanyl-phenyl)-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinoline::CHEMBL327790

SMILES CSc1ccc(cc1)C1CN2CCC[C@@H]2c2ccccc12

InChI Key InChIKey=YVKDUIAAPBKHMJ-MUMRKEEXSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50014237   

TargetSodium-dependent dopamine transporter(MOUSE)
Mcneil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50014237(6-(4-Methylsulfanyl-phenyl)-1,2,3,5,6,10b-hexahydr...)
Affinity DataKi:  0.390nMAssay Description:Tested in vitro for serotonin(5-HT) neuronal uptake inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(MOUSE)
Mcneil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50014237(6-(4-Methylsulfanyl-phenyl)-1,2,3,5,6,10b-hexahydr...)
Affinity DataKi:  0.680nMAssay Description:Tested in vitro for serotonin(5-HT) neuronal uptake inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(MOUSE)
Mcneil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50014237(6-(4-Methylsulfanyl-phenyl)-1,2,3,5,6,10b-hexahydr...)
Affinity DataKi:  0.680nMAssay Description:Tested in vitro for serotonin(5-HT) neuronal uptake inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(MOUSE)
Mcneil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50014237(6-(4-Methylsulfanyl-phenyl)-1,2,3,5,6,10b-hexahydr...)
Affinity DataKi:  1.80nMAssay Description:Tested in vitro for serotonin(5-HT) neuronal uptake inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(MOUSE)
Mcneil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50014237(6-(4-Methylsulfanyl-phenyl)-1,2,3,5,6,10b-hexahydr...)
Affinity DataKi:  2.90nMAssay Description:Tested in vitro for dopamine(DA) neuronal uptake inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(MOUSE)
Mcneil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50014237(6-(4-Methylsulfanyl-phenyl)-1,2,3,5,6,10b-hexahydr...)
Affinity DataKi:  2.90nMAssay Description:Tested in vitro for norepinephrine (NE) neuronal uptake inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(MOUSE)
Mcneil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50014237(6-(4-Methylsulfanyl-phenyl)-1,2,3,5,6,10b-hexahydr...)
Affinity DataKi:  23.5nMAssay Description:Tested in vitro for dopamine(DA) neuronal uptake inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(MOUSE)
Mcneil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50014237(6-(4-Methylsulfanyl-phenyl)-1,2,3,5,6,10b-hexahydr...)
Affinity DataKi:  36.8nMAssay Description:Tested in vitro for dopamine(DA) neuronal uptake inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(MOUSE)
Mcneil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50014237(6-(4-Methylsulfanyl-phenyl)-1,2,3,5,6,10b-hexahydr...)
Affinity DataKi:  37nMAssay Description:Tested in vitro for dopamine(DA) neuronal uptake inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed