BDBM50014247 (3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phenyl-piperidine::3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phenyl-piperidine(femoxetine)::CHEMBL94739::Femoxetine

SMILES: COc1ccc(OC[C@H]2CN(C)CC[C@@H]2c2ccccc2)cc1

InChI Key: InChIKey=OJSFTALXCYKKFQ-UHFFFAOYSA-N

Data: 27 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 27 hits for monomerid = 50014247   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rat)	BDBM50014247 ((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		9.08	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent dopamine transporter (Mouse)	BDBM50014247 ((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		9.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent serotonin transporter (Human)	BDBM50014247 ((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M1 (Human)	BDBM50014247 ((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent noradrenaline transporter (Mouse)	BDBM50014247 ((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Norepinephrine transporter (Rat)	BDBM50014247 ((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		121	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Human)	BDBM50014247 ((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M2 (Human)	BDBM50014247 ((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M2 (Human)	BDBM50014247 ((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		184	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M3 (Human)	BDBM50014247 ((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M5 (Human)	BDBM50014247 ((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Rat)	BDBM50014247 ((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		407	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M4 (Human)	BDBM50014247 ((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50014247 ((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50014247 ((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		650	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent noradrenaline transporter (Human)	BDBM50014247 ((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		760	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent dopamine transporter (Mouse)	BDBM50014247 ((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		1.04E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent dopamine transporter (Rat)	BDBM50014247 ((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		1.04E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-arrestin-2 (Bovine)	BDBM50014247 ((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		1.91E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Human)	BDBM50014247 ((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		1.97E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent dopamine transporter (Human)	BDBM50014247 ((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		2.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50014247 ((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		2.29E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Rat)	BDBM50014247 ((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine 1D receptor (Bovine)	BDBM50014247 ((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		3.72E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM50014247 ((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1B (Rat)	BDBM50014247 ((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		9.33E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 3A (Rat)	BDBM50014247 ((3R,4S)-3-(4-Methoxy-phenoxymethyl)-1-methyl-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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