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BDBM50014272 CHEMBL3221245

SMILES: CC1=C(C(C=C(N1)c1ccc(C)cc1)c1ccc(C)cc1)C(=O)SC(C)(C)C

InChI Key: InChIKey=LLDHTTUPQLNXDV-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50014272   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated calcium channel


(Homo sapiens (Human))
BDBM50014272
PNG
(CHEMBL3221245)
Show SMILES CC1=C(C(C=C(N1)c1ccc(C)cc1)c1ccc(C)cc1)C(=O)SC(C)(C)C
Show InChI InChI=1/C25H29NOS/c1-16-7-11-19(12-8-16)21-15-22(20-13-9-17(2)10-14-20)26-18(3)23(21)24(27)28-25(4,5)6/h7-15,21,26H,1-6H3
PDB
MMDB

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Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...


J Med Chem 57: 4313-23 (2014)


Article DOI: 10.1021/jm500263v
BindingDB Entry DOI: 10.7270/Q22R3T6K
More data for this
Ligand-Target Pair