BDBM50014320 8-Chloro-5-(4-chloro-phenyl)-5H-indeno[1,2-d]pyrimidine(LY 113174)::CHEMBL101324::LY-113174

SMILES: Clc1ccc(cc1)C1c2ccc(Cl)cc2-c2ncncc12

InChI Key: InChIKey=ZKGILAGEAKMIIG-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50014320   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 19A1 (Rattus norvegicus)	BDBM50014320 (8-Chloro-5-(4-chloro-phenyl)-5H-indeno[1,2-d]pyrim...) Show SMILES Clc1ccc(cc1)C1c2ccc(Cl)cc2-c2ncncc12 Show InChI InChI=1S/C17H10Cl2N2/c18-11-3-1-10(2-4-11)16-13-6-5-12(19)7-14(13)17-15(16)8-20-9-21-17/h1-9,16H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for Cytochrome P450 19A1				J Med Chem 33: 2933-42 (1990) Article DOI: 10.1021/jm00173a001 BindingDB Entry DOI: 10.7270/Q2VM4CW9
					More data for this Ligand-Target Pair