BDBM50014345 CHEMBL11804::Sodium; (E)-(3R,5S)-9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-nona-6,8-dienoate::Sodium; 9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-nona-6,8-dienoate
SMILES [#6]-n1nnnc1\[#6](\[#6]=[#6]\[#6@@H](-[#8])-[#6]-[#6@@H](-[#8])-[#6]-[#6](-[#8-])=O)=[#6](\c1ccc(F)cc1)-c1ccc(F)cc1
InChI Key InChIKey=HPFIYXJJZZWEPC-MMKWGKFASA-M
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50014345
Affinity DataIC50: 1.60E+3nMAssay Description:Compound was evaluated for inhibitory activity against HMG-CoA reductase in adrenal cell preparationMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Ability to inhibit microsomal preparation of HMG-CoA reductase in rat liver.More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Compound was evaluated for inhibitory activity against HMG-CoA reductase in spleen cell preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Compound was evaluated in vitro for inhibitory activity against isolated enzyme HMG-CoA reductaseMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Compound was evaluated for inhibitory activity against HMG-CoA reductase in HepG2 cellsMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Compound was evaluated for inhibitory activity against HMG-CoA reductase in liver cell preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Compound was evaluated for inhibitory activity against rat hepatocyteMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Compound was evaluated for inhibitory activity against HMG-CoA reductase in bovine occular cell preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.34E+3nMAssay Description:Compound was evaluated for inhibitory activity against HMG-CoA reductase in testes cell preparationMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair