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BDBM50014754 1-[(4-Chloro-phenyl)-(4-methoxy-phenyl)-methyl]-1H-imidazole::CHEMBL135063

SMILES: COc1ccc(cc1)C(c1ccc(Cl)cc1)n1ccnc1

InChI Key: InChIKey=FCDZKZLCSZAFRA-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50014754   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 19A1


(Rattus norvegicus)
BDBM50014754
PNG
(1-[(4-Chloro-phenyl)-(4-methoxy-phenyl)-methyl]-1H...)
Show SMILES COc1ccc(cc1)C(c1ccc(Cl)cc1)n1ccnc1
Show InChI InChI=1S/C17H15ClN2O/c1-21-16-8-4-14(5-9-16)17(20-11-10-19-12-20)13-2-6-15(18)7-3-13/h2-12,17H,1H3
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Similars

Article
PubMed
n/an/an/an/a 8.40n/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome


J Med Chem 33: 416-29 (1990)


Article DOI: 10.1021/jm00163a065
BindingDB Entry DOI: 10.7270/Q2WM1F0N
More data for this
Ligand-Target Pair