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BDBM50014758 Bis-(4-chloro-phenyl)-pyridin-3-yl-methanol::CHEMBL135115

SMILES: OC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1cccnc1

InChI Key: InChIKey=NBNTWDUNCHRWMT-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50014758   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 19A1


(Rattus norvegicus)
BDBM50014758
PNG
(Bis-(4-chloro-phenyl)-pyridin-3-yl-methanol | CHEM...)
Show SMILES OC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1cccnc1
Show InChI InChI=1S/C18H13Cl2NO/c19-16-7-3-13(4-8-16)18(22,15-2-1-11-21-12-15)14-5-9-17(20)10-6-14/h1-12,22H
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Article
PubMed
n/an/an/an/a 150n/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome


J Med Chem 33: 416-29 (1990)


Article DOI: 10.1021/jm00163a065
BindingDB Entry DOI: 10.7270/Q2WM1F0N
More data for this
Ligand-Target Pair