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BDBM50014759 5-[Bis-(4-chloro-phenyl)-imidazol-1-yl-methyl]-thiazole::CHEMBL133262

SMILES: Clc1ccc(cc1)C(c1cncs1)(c1ccc(Cl)cc1)n1ccnc1

InChI Key: InChIKey=SAJLCBSYYJJDBT-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50014759   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 19A1


(Rattus norvegicus)
BDBM50014759
PNG
(5-[Bis-(4-chloro-phenyl)-imidazol-1-yl-methyl]-thi...)
Show SMILES Clc1ccc(cc1)C(c1cncs1)(c1ccc(Cl)cc1)n1ccnc1
Show InChI InChI=1S/C19H13Cl2N3S/c20-16-5-1-14(2-6-16)19(18-11-23-13-25-18,24-10-9-22-12-24)15-3-7-17(21)8-4-15/h1-13H
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KEGG

UniProtKB/SwissProt

GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 17n/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome


J Med Chem 33: 416-29 (1990)


Article DOI: 10.1021/jm00163a065
BindingDB Entry DOI: 10.7270/Q2WM1F0N
More data for this
Ligand-Target Pair