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BDBM50014778 Bis-(4-chloro-phenyl)-(1H-pyrazol-4-yl)-methanol::CHEMBL137589

SMILES: OC(c1cn[nH]c1)(c1ccc(Cl)cc1)c1ccc(Cl)cc1

InChI Key: InChIKey=MIRUIVSVSJTQDQ-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50014778   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 19A1


(Rattus norvegicus)
BDBM50014778
PNG
(Bis-(4-chloro-phenyl)-(1H-pyrazol-4-yl)-methanol |...)
Show SMILES OC(c1cn[nH]c1)(c1ccc(Cl)cc1)c1ccc(Cl)cc1
Show InChI InChI=1S/C16H12Cl2N2O/c17-14-5-1-11(2-6-14)16(21,13-9-19-20-10-13)12-3-7-15(18)8-4-12/h1-10,21H,(H,19,20)
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KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 30n/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome


J Med Chem 33: 416-29 (1990)


Article DOI: 10.1021/jm00163a065
BindingDB Entry DOI: 10.7270/Q2WM1F0N
More data for this
Ligand-Target Pair