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BDBM50014781 1-[(2-Methoxy-phenyl)-phenyl-methyl]-1H-imidazole::CHEMBL137002

SMILES: COc1ccccc1C(c1ccccc1)n1ccnc1

InChI Key: InChIKey=HFOVUZVEKOQRFF-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50014781   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 19A1


(Rattus norvegicus)
BDBM50014781
PNG
(1-[(2-Methoxy-phenyl)-phenyl-methyl]-1H-imidazole ...)
Show SMILES COc1ccccc1C(c1ccccc1)n1ccnc1
Show InChI InChI=1S/C17H16N2O/c1-20-16-10-6-5-9-15(16)17(19-12-11-18-13-19)14-7-3-2-4-8-14/h2-13,17H,1H3
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KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 66n/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome


J Med Chem 33: 416-29 (1990)


Article DOI: 10.1021/jm00163a065
BindingDB Entry DOI: 10.7270/Q2WM1F0N
More data for this
Ligand-Target Pair