BDBM50014796 1-[(4-Methoxy-phenyl)-p-tolyl-methyl]-1H-imidazole::CHEMBL335050

SMILES: COc1ccc(cc1)C(c1ccc(C)cc1)n1ccnc1

InChI Key: InChIKey=YHCDAJQYADLADQ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50014796   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 19A1 (Rattus norvegicus)	BDBM50014796 (1-[(4-Methoxy-phenyl)-p-tolyl-methyl]-1H-imidazole...) Show SMILES COc1ccc(cc1)C(c1ccc(C)cc1)n1ccnc1 Show InChI InChI=1S/C18H18N2O/c1-14-3-5-15(6-4-14)18(20-12-11-19-13-20)16-7-9-17(21-2)10-8-16/h3-13,18H,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome				J Med Chem 33: 416-29 (1990) Article DOI: 10.1021/jm00163a065 BindingDB Entry DOI: 10.7270/Q2WM1F0N
					More data for this Ligand-Target Pair