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BDBM50014803 4-[Bis-(4-chloro-phenyl)-methyl]-4H-[1,2,4]triazole::CHEMBL135563

SMILES: Clc1ccc(cc1)C(c1ccc(Cl)cc1)n1cnnc1

InChI Key: InChIKey=AIKBWGFUDXJFEP-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50014803   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 19A1


(Rattus norvegicus)
BDBM50014803
PNG
(4-[Bis-(4-chloro-phenyl)-methyl]-4H-[1,2,4]triazol...)
Show SMILES Clc1ccc(cc1)C(c1ccc(Cl)cc1)n1cnnc1
Show InChI InChI=1S/C15H11Cl2N3/c16-13-5-1-11(2-6-13)15(20-9-18-19-10-20)12-3-7-14(17)8-4-12/h1-10,15H
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KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 9.30n/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
In vitro Cytochrome P450 19A1 inhibition concentration to decrease aromatization of androstenedione in rat ovarian microsome


J Med Chem 33: 416-29 (1990)


Article DOI: 10.1021/jm00163a065
BindingDB Entry DOI: 10.7270/Q2WM1F0N
More data for this
Ligand-Target Pair