BDBM50014853 CHEMBL277998::N-((S)-3-Hydroxy-1,2-dimethoxy-10-methylsulfanyl-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-acetamide::N-(3-Hydroxy-1,2-dimethoxy-10-methylsulfanyl-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-acetamide::cid_434973

SMILES COc1c(O)cc2CC[C@H](NC(C)=O)c3cc(=O)c(SC)ccc3-c2c1OC

InChI Key InChIKey=PKYOHQGXPPVIGD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50014853   

TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50014853(CHEMBL277998 | cid_434973 | N-(3-Hydroxy-1,2-dimet...)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin beta-2B chain(Bovine)
Niddk

Curated by ChEMBL
LigandPNGBDBM50014853(CHEMBL277998 | cid_434973 | N-(3-Hydroxy-1,2-dimet...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory effect on the polymerization of purified bovine brain tubulin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetNuclear receptor subfamily 0 group B member 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50014853(CHEMBL277998 | cid_434973 | N-(3-Hydroxy-1,2-dimet...)
Affinity DataIC50: 6.75E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetSteroidogenic factor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50014853(CHEMBL277998 | cid_434973 | N-(3-Hydroxy-1,2-dimet...)
Affinity DataIC50: 6.75E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay