BDBM50014960 1-Benzyl-1,3-dihydro-imidazole-2-thione::1-Benzyl-1H-imidazole-2-thiol::CHEMBL164791

SMILES S=c1[nH]ccn1Cc1ccccc1

InChI Key InChIKey=AOCFYLGZVCPZML-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50014960   

TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014960(1-Benzyl-1,3-dihydro-imidazole-2-thione | 1-Benzyl...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50014960(1-Benzyl-1,3-dihydro-imidazole-2-thione | 1-Benzyl...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of Dopamine beta hydroxylase in spontaneously hypertensive rats; Value range from 8.9-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014960(1-Benzyl-1,3-dihydro-imidazole-2-thione | 1-Benzyl...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of Dopamine beta hydroxylase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Homo sapiens (Human))
Molecular Simulations

Curated by ChEMBL
LigandPNGBDBM50014960(1-Benzyl-1,3-dihydro-imidazole-2-thione | 1-Benzyl...)
Affinity DataIC50:  3.31E+4nMAssay Description:Inhibition of dopamine beta hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50014960(1-Benzyl-1,3-dihydro-imidazole-2-thione | 1-Benzyl...)
Affinity DataIC50:  3.31E+4nMAssay Description:Inhibition of dopamine beta-hydroxylase (DbetaH) in hypertensive rats when administered orally (or) intraperitoneallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Homo sapiens (Human))
Molecular Simulations

Curated by ChEMBL
LigandPNGBDBM50014960(1-Benzyl-1,3-dihydro-imidazole-2-thione | 1-Benzyl...)
Affinity DataIC50:  3.31E+4nMAssay Description:Inhibition of dopamine beta-hydroxylase (DbetaH) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014960(1-Benzyl-1,3-dihydro-imidazole-2-thione | 1-Benzyl...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibitory Concentration against bovine v (DBH); Range is between (20-46).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed