BDBM50014969 1-(3-Fluoro-benzyl)-1,3-dihydro-imidazole-2-thione::CHEMBL63907

SMILES Fc1cccc(Cn2cc[nH]c2=S)c1

InChI Key InChIKey=BVQNVINXXGBFBH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50014969   

TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014969(1-(3-Fluoro-benzyl)-1,3-dihydro-imidazole-2-thione...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibitory activity was determined against bovine dopamine beta-hydroxylase(DBH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50014969(1-(3-Fluoro-benzyl)-1,3-dihydro-imidazole-2-thione...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibitory Concentration against bovine Dopamine beta hydroxylase (DBH); Range is between (4.9-6.5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Homo sapiens (Human))
Molecular Simulations

Curated by ChEMBL
LigandPNGBDBM50014969(1-(3-Fluoro-benzyl)-1,3-dihydro-imidazole-2-thione...)
Affinity DataIC50:  5.62E+3nMAssay Description:Inhibition of dopamine beta hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Homo sapiens (Human))
Molecular Simulations

Curated by ChEMBL
LigandPNGBDBM50014969(1-(3-Fluoro-benzyl)-1,3-dihydro-imidazole-2-thione...)
Affinity DataIC50:  5.62E+3nMAssay Description:Inhibition of dopamine beta-hydroxylase (DbetaH) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Rattus norvegicus)
University Of Illinois

Curated by ChEMBL
LigandPNGBDBM50014969(1-(3-Fluoro-benzyl)-1,3-dihydro-imidazole-2-thione...)
Affinity DataIC50:  5.62E+3nMAssay Description:Inhibition of dopamine beta-hydroxylase (DbetaH) in hypertensive rats when administered orally (or) intraperitoneallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed