BDBM50015367 CHEMBL3264602

SMILES COc1cc2ccc(cc2cc1OC)C(O)(C(C)C)c1ccncc1

InChI Key InChIKey=WLSFHVCGANYCRC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50015367   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015367(CHEMBL3264602)
Affinity DataIC50: 60nMAssay Description:Inhibition of rat testicular microsome CYP17 lyase activity using 17alpha-hydroxypregnenolone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015367(CHEMBL3264602)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human hepatocyte microsome CYP3A4 using testosterone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed