BDBM50016233 CHEMBL3262475

SMILES NC(=O)COc1cccc(\C=C2/SC(=S)N(CC(O)=O)C2=O)c1

InChI Key InChIKey=SFYXCISZCOXLBJ-YHYXMXQVSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50016233   

TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50016233(CHEMBL3262475)
Affinity DataIC50:  130nMAssay Description:Inhibition of bovine aldose reductase assessed as oxidation of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50016233(CHEMBL3262475)
Affinity DataIC50:  64nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50016233(CHEMBL3262475)
Affinity DataIC50:  7.17E+5nMAssay Description:Inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system using pNPP as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed