BDBM50016676 CHEMBL293264::N-Hydroxy-4-(4-methoxy-phenyl)-N-phenethyl-butyramide

SMILES COc1ccc(CCCC(=O)N(O)CCc2ccccc2)cc1

InChI Key InChIKey=KQWFHBABTNKSHN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50016676   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016676(CHEMBL293264 | N-Hydroxy-4-(4-methoxy-phenyl)-N-ph...)
Affinity DataIC50:  2.50E+3nMAssay Description:Invitro inhibition of rat platelet 12-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016676(CHEMBL293264 | N-Hydroxy-4-(4-methoxy-phenyl)-N-ph...)
Affinity DataIC50:  250nMAssay Description:Invitro inhibition of polymorphonuclear leukocyte derived human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50016676(CHEMBL293264 | N-Hydroxy-4-(4-methoxy-phenyl)-N-ph...)
Affinity DataIC50:  120nMAssay Description:In vitro inhibition of rat polymorphonuclear leukocyte 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed