BDBM50016886 1,5-Dimethyl-2,3,4,4a,10,10a-hexahydro-1H-9-oxa-1-aza-phenanthren-8-ol::CHEMBL422024

SMILES CN1CCC[C@H]2[C@H]1COc1c(O)ccc(C)c21

InChI Key InChIKey=LJXJXZFDHJGEBQ-WDEREUQCSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50016886   

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50016886(1,5-Dimethyl-2,3,4,4a,10,10a-hexahydro-1H-9-oxa-1-...)
Affinity DataIC50:  76nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]-8-Hydroxy-2-(di-n-propylamino)tetralin binding to 5-hydroxytryptamine 1A receptor ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50016886(1,5-Dimethyl-2,3,4,4a,10,10a-hexahydro-1H-9-oxa-1-...)
Affinity DataIC50:  1.02E+3nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]-clonidine binding to alpha-2 adrenergic receptor at 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50016886(1,5-Dimethyl-2,3,4,4a,10,10a-hexahydro-1H-9-oxa-1-...)
Affinity DataIC50:  26nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(2) dopamine receptor(BOVINE)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50016886(1,5-Dimethyl-2,3,4,4a,10,10a-hexahydro-1H-9-oxa-1-...)
Affinity DataIC50:  170nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]spiperone binding dopamine receptor at 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50016886(1,5-Dimethyl-2,3,4,4a,10,10a-hexahydro-1H-9-oxa-1-...)
Affinity DataIC50:  97nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]-ketanserin binding to 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed